New Medication For Post Concussion Headaches

Head injury victims taking the blood pressure drug prazosin, branded as Minipress, experienced half as many headaches as those on an inactive placebo. Washington state Veterans Administration healthcare researchers performed a randomized pilot study of the drug on 32 military veterans and active duty personnel. An additional 16 received a placebo medication.

The data revealed a 44% reduction in headache frequency for those taking prazosin compared with controls. The percentage of participants experiencing a 50% reduction in their headaches was 70% for those taking the drug vs 29% for those on the placebo. Of most import, the prazosin significantly reduced the impact of headaches on the participants’ everyday lives.

This preliminary study will be followed by larger, double-blinded randomized trials, but the initial results are encouraging indeed.

https://headachejournal.onlinelibrary.wiley.com/doi/10.1111/head.14529

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