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Microfluidic Test System Allows Multi-Organ Testing

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Microfluidic Test System Allows Multi-Organ Testing

D
Dr. Howard Smith Reports

2 Views • Nov 06, 2023

Description



A literal “body on a chip” permits the testing of drugs and other biologics on multiple organs simultaneously. Developed at Northwestern University, the so-called Lattice device permits the simultaneous testing of potential therapeutics on up to 8 different organ systems. The organ tissue samples or artificially-generated organoids are placed in separate wells, and the medications to be tested flow into each well via micro-channels. Another function of Lattice permits testing the effects of one organ on another or others. For example, a hormone-producing organ in one well is bathed in nutrient media that picks up the hormones and carries them to other wells containing other organs. It’s a brave new world, and it’s coming……Someday soon.

https://pubs.rsc.org/en/Content/ArticleLanding/2023/LC/D3LC00378G

#microfluidics #organoids #drugtesting #lattice