Gallbladder

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The gallbladder is a small pouch that sits just under the liver. The gallbladder stores bile produced by the liver. After meals, the gallbladder is empty and flat, like a deflated balloon. Before a meal, the gallbladder may be full of bile and about the size of a small pear.

In response to signals, the gallbladder squeezes stored bile into the small intestine through a series of tubes called ducts. Bile helps digest fats, but the gallbladder itself is not essential. Removing the gallbladder in an otherwise healthy individual typically causes no observable problems with health or digestion yet there may be a small risk of diarrhea and fat malabsorption.

Diagnostic Studies. Laboratory tests helpful in the diagnosis of gallbladder and biliary tract diseases include evaluation of direct bilirubin and alkaline phosphatase, both of which are elevated in biliary tract disease. The presence of bile in the urine is indicative of biliary obstruction.

One of the most common radiologic techniques for diagnosis of gallbladder disease is ultrasonography. It is a noninvasive procedure that can help differentiate between biliary obstruction and liver disease. Abnormal patterns on the graph can show an enlarged gallbladder, obstruction of the common bile duct, dilatation in the biliary tree, and the presence of stones in the gallbladder and common bile duct. Ultrasonography has the advantages of being quick, requiring no special preparation of the patient, and avoiding the risks of exposure to radiation from x-rays.

Another commonly used radiologic study is radionuclide imaging, using an intravenous injection of 99Tc iminodiacetic acid (HIDA) or some other radioisotope that has an affinity for the biliary tree and concentrates at that site.

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